The Reck-Peterson lab investigates mechanisms of intracellular transport in health and disease spanning molecular, cellular and organismal scales. Our current projects can be grouped into five major areas: 1) the function and mechanism of dynein and kinesin microtubule motors, 2) the molecular basis of Parkinson’s Disease, a disease linked to defects in intracellular transport, 3) organelle contacts and organelle hitchhiking, 4) the cell biology of secondary metabolism in filamentous fungi, and 5) the functional consequences of RNA recoding of molecular machines.